CAS No. 153851-71-9

The project standards | appearance: white to light yellow crystalline powder of | | content determination: 98% than curl: - 26.0 ° to - 36.0 | | ° ph: ph 4.5-6.0 | should be single impurity: < 1.0% | | total: < 3.0% impurities tetrahydrofuran and acetone: THF less than 0.072%, acetone less than 0.5% | dry weightlessness: no higher than 1.0% | ablaze burning scraps: not cross over 0.2% | | heavy metal: not cross over 20ppm than APei south side chain belong to medicine pharmacy raw materials can be used in the production of antibiotic drugs than APei south. APei south (than Biapenem, LJC 10627) by a Japanese Lederle and U.S. cyanogen ammonia in 1989, the company developed the injectable antibiotics carbon penicillin xi kind, has completed in Japan Ⅲ period clinical research, waiting for the approval of listings. This product is the most striking features in 2 - a S has 2-ring three of triazoles 1 beta methyl carbon penicillium ene. Structureactivity relationship study showed that the side chain quaternary ammonium salt cationic center of existence is the key to the outer membrane permeability effect, make than APei south inhibit pseudomonas aeruginosa and the activity of anaerobic bacteria for Imipenem (Imipenem) 2 ~ 4 times, inhibit drug resistance pseudomonas aeruginosa activity for beauty e.faecalis (Meropenem) 4 ~ 8 times for fixed bacili, he shall effective means of anaerobic bacteria cephalosporins.